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Running head: Circadian Photoreception A look at circadian photoreception in blind people

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Research Assistant
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Advanced
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psychology
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documents in English
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case study
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4 pages
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Advanced
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  1. Abstract:.
  2. How Do Blind People Know the Time of Day?
  3. A look at circadian photoreception in blind people.
  4. Intrinsically photosensitive retinal ganglion cells
  5. Protein synthesis and degradation in the SCN
  6. Conclusion
  7. References

In humans, the suprachiasmatic nucleus (SCN) controls the body's circadian rhythms. Each day, sighted people have the opportunity to reset their internal clock based on the amount of ambient light entering their retinas. The retina contains a subset of retinal ganglion cells specialized in regulating the body's rhythms. These ganglion cells project to the SCN from both eyes via the retinohypothalamic pathway. But how do completely blind people synchronize with their environment? Non-photic cues may help blind people sense the passage of time, but they are not always enough to regulate the body's cycle of body temperature and hormones.

Keywords: Intrinsically photosensitive retinal ganglion cells (ipRGCs), retina, olivary pretectal nucleus (OPN)

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