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Biology of Ageing

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Level
General public
Study
medical...
School/University
UFMG

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documents in English
Format
.ppt
Type
presentations
Pages
48 slides
Level
General public
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  1. The life course approach to the understanding of aging
  2. The evolutionary biological theory of aging: A satisfactory explanation for why we age
  3. Classes of gene action that escape the force of natural selection
  4. Environmentally triggered diapause and caloric restriction
  5. Human progeroid mutations
  6. Conclusions
  7. Bibliography

It is useful to think of organisms as protein-synthesizing factories. If that factory is to function at very high levels of efficiency and stability for very long periods of time, the builder should start with an excellent set of blueprints (hence the importance of understanding the constitutional genomes of individual patients), hire engineers and supervisors to oversee its construction and maturation Ensure that the factory functions in a safe environment (hence the importance of protecting patients from teratogens, mutagens, carcinogens, and candidate "gerontogens," such as tobacco smoke), and, finally, initiate rigorous regimens of quality control throughout the life span of the factory (hence the importance of such biologic processes as DNA repair and the detection, reconstitution, and turnover of aberrant proteins).

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