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PERCOCET: How it works

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  1. Background
  2. Structures
  3. How it works
  4. Conclusion
  5. References

Percocet is a well known pain killer used to treat pain for moderate to severe sufferers of a wide variety of ailments. Percocet, or similarly composed products containing narcotics, are prescribed by doctors quite often for various forms of serious pain (ranging from severe, chronic, cases such as cancer pain to common cases such as pain induced by wisdom teeth extraction). The drug is composed of two main ingredients: Oxycodone, an opioid agonist, and acetaminophen, a well known and widely used analgesic. In colloquial terms, this drug is simply a narcotic drug and Tylenol.

[...] In this case, Oxycodone acts as a much like the endogenous opioids, where it binds to a protein (receptor) and changes its properties Oxycodone's structure, which is similar to that of morphene and the endogenous opiods, is thought to fit these receptor binding sites directly (unlike, say, heroin, which is metabolized into morphine which then binds to the receptor). This bond is maintained by intermolecular forces and is not covalent; it can easily be reversed. In binding to both the mu- and kappa- receptors, Oxycodone changes their shape allowing the to propagate into the cell via changes in GDP/GTP This allows further cell processes to occur, producing, among other things, the desired analgesia. [...]


[...] PERCOCET: How it works Background Percocet is a well known pain killer used to treat pain for moderate to severe sufferers of a wide variety of ailments. Percocet, or similarly composed products containing narcotics, are prescribed by doctors quite often for various forms of serious pain (ranging from severe, chronic, cases such as cancer pain to common cases such as pain induced by wisdom teeth extraction). The drug is composed of two main ingredients: Oxycodone, an opioid agonist, and acetaminophen, a well known and widely used analgesic. [...]

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