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The progress that has been made in research development regarding how the body produces and regulates cholesterol

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  1. Introduction.
  2. Cholesterol Metabolism.
  3. Regulation of Cholesterol Synthesis.
  4. The Body's Use of Cholesterol.
  5. Cellular Sterol Content.
  6. Bile Acid Synthesis.
  7. Drugs to Lower Cholesterol.
  8. Conclusion

In recent years, cholesterol has become a topic of paramount concern for public health. Research on cholesterol has shown that increased levels of this compound in the bloodstream can increase an individual's risk for the development of a host of chronic health problems including coronary heart disease and atherosclerosis. Despite the fact that cholesterol has been viewed as a negative component of an individual's diet, research on the compound clearly shows that cholesterol is essential for the proper function of the human body. As such, there is a clear impetus for individuals to understand the benefits and drawbacks of cholesterol in the human body.

[...] Through a careful consideration of what has been written on these topics a more integral understanding of cholesterol and the need to regulate this substance in the human body will be elucidated. Cholesterol Metabolism What is perhaps most interesting about the process of cholesterol metabolism is that while many laymen assume that cholesterol only comes from the specific foods that the eat?meaning that a reduction in dietary cholesterol will reduce the level of cholesterol in the body?research on the synthesis of cholesterol shows that this compound is made by the human body. [...]

[...] Cellular Sterol Content While the above information provides a clear understanding of how the body regulates the production, transportation and excretion of cholesterol, what is not addressed in this information is how the cell regulates the production of cholesterol overall. In this context sterol is needed for the production of cholesterol. To capture the sterol needed the cell activates LDL receptors on the cell surface. As the need for cholesterol increases, so too do the LDL activation sites on the cell. [...]

[...] For individuals that produce too much LDL cholesterol as a result of a genetic defect, or for those that consume too much cholesterol in their diet, statins can notably reduce the development of heart disease and atherosclerosis. Even though statins are among the most widely used drugs for controlling cholesterol levels, researchers have noted that these drugs have serious side effects. Researchers have noted that the use of statins can cause rhabdomyolysis, In this condition muscle tissue begins to degrade and is released into the blood stream. [...]

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