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Cost literature review: Assisted reproductive techniques and In-vitro fertilization

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  1. Introduction.
  2. Financing of assisted reproductive technology.
    1. Should health insurance cover the cost of infertility treatment?
    2. Limited or comprehensive coverage for infertility treatments and services.
    3. The aims of the insurance coverage mandates.
  3. Prognostic factors, outcomes, and cost-effectiveness of frozen embryo donation and adoption.
    1. Prognostic factors of frozen embryo donation and adoption.
    2. Outcomes of embryo donation and adoption.
    3. Success rates of frozen donation and adoption.
    4. Cost-effectiveness of frozen embryo donation and adoption.
  4. Cost of embryo adoption.
  5. Charges of obtaining embryos for transfer.
    1. Cost of retesting and screening of donors and recipient.
    2. Cost of identifying, recruiting, and counseling potential donors.
    3. Charges of frozen embryo per transfer cycle.
  6. Conclusion.

According to the American Society of Reproductive Medicine, fertility problems affect 7.3 million of women and their partners in the United States. That compromises about twelve percent of the population of reproductive age (American Society for Reproductive Medicine, 2008). The majority of patients with fertility problems (85-90%) are treated with conventional medical therapies such as medication or surgery. In-vitro fertilization (IVF) and other modern assisted reproductive techniques (ART) of infertility treatment, including frozen embryo donation and adoption, account for less than three percent of infertility services and comprise only 0.07% of the U.S healthcare cost (American Society for Reproductive Medicine, 2008).

[...] It also compares the success rates of ED&A to the success rates of fresh IVF cycles using non-donor eggs or embryos and to IVF cycles with oocyte donation. We define the outcomes as the average live-birth rate per transfer cycle. The cost is defined as the cost per live birth and the average treatment costs per cycle Success Rates of Frozen Donation and Adoption In 2005, a total of 134,260 ART procedures were reported. These performed procedures produced 38,910 live births and 52,041 infants. Of those infants born through ART, forty nine percent were born in multiple-birth deliveries (Centers for Disease Control and Prevention, 2008). [...]

[...] The cost of ED&A is expected to be less expensive compared to the cost of conventional IVF procedures and IVF procedures with oocyte donation, where many of the most expensive parts of an IVF cycle, including the fertility medications, the egg retrieval, and the fertilization and culture of the embryos do not need to be performed. Although ART procedures that use embryos created from freshly fertilized donor eggs document high success rates of live-birth (Centers for Disease Control and Prevention, 2008), IVF procedures with oocyte donation are associated with high cost. [...]

[...] Although ED&A awareness campaigns exist to help both donating and adopting families learn more about this life building option, we found no literature that reported the cost of targeting identifying, recruiting, and counseling potential donors. Charges of Frozen Embryo per Transfer Cycle As noted above, the costs of ED&A and embryo transfer are significantly less compared to the costs of conventional IVF and IVF with oocyte donation. The charges of the frozen embryo transfer cycle vary from program to program. [...]

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