Neurodegeneration process, Parkinson disease, Alzheimer disease, neurodegenerative disease, memory, central nervous system, dementia, degenerative brain conditions
Neurodegeneration refers to the gradual loss of structure and operation of neurons, including death of neurons. The theme of the current paper is to discuss two diseases linked with the neurodegeneration process: Parkinson and Alzheimer disease. Also, the differences between the two diseases will be discussed.
[...] Parkinson's disease is linked with extrapyramidal symptoms bur Alzheimer's disease is related with continued loss of cognitive thinking which advances until the patient is unable to undertake normal daily activities. References Dorsey, E. R., Constantinescu, R., Thompson, J. P., Biglan, K. M., Holloway, R. G., Kieburtz, K., & Tanner, C. M. (2007). Projected number of people with Parkinson disease in the most populous nations through 2030. Neurology, 384-386. Hy, L. X., & Keller, D. M. (2000). [...]
[...] Dementia is evident in the advanced phases of Parkinson's disease. The causes are unknown but are believed to be both environmental and genetic factors (Campdelacreu, 2014). The motor symptoms of arise due to death of substantia nigra cells, which leads to insufficient dopamine in the areas. Alzheimer's disease Alzheimer's disease is a gradual neurodegenerative condition that breaks up one's memory. It is a popular source of dementia collection of brain disorders that cause loss of social and intellectual skills). The symptoms became serious with time, interfering with daily life activities. [...]
[...] Prevalence of AD among whites A summary by levels of severity. Neurology, 198-204. Campdelacreu, J. (2014). Parkinson's disease and Alzheimer disease: environmental risk factors. Neurología (English Edition), 541- 549. Yan, M. H., Wang, X., & Zhu, X. (2013). Mitochondrial defects and oxidative stress in Alzheimer disease and Parkinson disease. Free Radical Biology and Medicine 90-101. [...]
[...] Little is known about Alzheimer's disease treatment, but research shows that acetylcholinesterase inhibitors can be used to slow the progression of the disorder after a definite diagnosis is recognized. Also, studies on prevention suggest that conducting mental exercises like reading and regularly stimulating the mind reduces the probability of acquiring Alzheimer's disease. It is widely reported that a combination of environmental triggers and genetic susceptibility factors are the causes of later start of sporadic Alzheimer's disease (Campdelacreu, 2014). It is believed that slow inflammatory process and oxidative damage are the primary mechanisms of operation. [...]
[...] However, the two disease are not related but have similarities. Both conditions start late in life, mainly after age 50 (Dorsey et al., 2007). Both conditions are neurodegenerative, which implies that they cause damage and death of brain cells (neurons). Also, they are both progressive, so their symptoms get worse over time. However, they two diseases have differences in their symptoms, causes, physical and biological manifestations (pathophysiology), and treatment. According to Yan, Wang, and Zhu (2013), both conditions are associated with “oxidative stress”. [...]
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