An acquired, slowly progressive depigmenting condition in small or large areas of the skin due to the disappearance of previously active melanocytes
Focal (including segmental) vitiligo: 1 to a few scattered macules, occasionally in a dermatomal distribution
Generalized vitiligo: Many widespread macules (most common form)
Universal vitiligo: Little remaining normal pigment
[...] MEDICATION (DRUGS) First Line Focal or segmental vitiligo - A midpotency steroid cream can be applied daily for 3-4 months. If no response, advance to high-potency steroids. Clobetasol (Temovate) cream applied daily for 2 months (every other day on the face). Treatment may be resumed following a 1-4-month respite. - Phototherapy with narrow band UVB 2 times per week. Generalized vitiligo: - Oral systemic steroids, e.g., betamethasone 5 mg given 2 days in a row, then held the remainder of the week. [...]
[...] Focal (including segmental) vitiligo: 1 to a few scattered macules, occasionally in a dermatomal distribution - Generalized vitiligo: Many widespread macules (most common form) - Universal vitiligo: Little remaining normal pigment - Acrofacial: Affects distal fingers and facial orifices System(s) Affected: Skin/Exocrine Synonym(s): Hypomelanosis; Depigmentation ALERT Pediatric Considerations Childhood vitiligo is a distinct subset of vitiligo. Higher incidence of focal vitiligo. Also higher incidence of autoimmune and endocrine disease. Response is poor to topical psoralen plus ultraviolet exposure (PUVA) therapy, but can be tried. [...]
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